Attempt to quantitate relation between cardiac function and infarct size in acute myocardial infarction.

In 82 patients with acute myocardial infarction, observed haemodynamic changes were compared with the average maximal serum enzyme rise and the infarct size, as calculated from serial determinations of creatine phosphokinase concentration. For this purpose, patients were divided into 3 groups according to their pulmonary artery end-diastolic pressure at the time of admission. There were I9 patients in group I with pulmonary artery end-diastolic pressure <12 mmHg; they had an average infarction size of I7g and no impairment of cardiac function. In the 35 patients in group II with pulmonary artery end-diastolic pressure